INSULIN

RI+NPH BID下：
早ri影嚮中午
早nph影嚮下午／晚上

晚nph影嚮早上

巳進CELL的GLUCOSE不會因藥效過而又再SHIFT出來

早上多打之ＲＩ多少Ｕ要記下來，
改成以後晚上ＮＰＨ的量

PHARMACODYNAMICS / KINETICS — Note: Rate of absorption, onset, and duration of activity may be affected by site of injection, exercise, presence of lipodystrophy, local blood supply, and/or temperature.
Excretion: Urine

RI:Onset 0.5 hours, Peak: 2.5-5 hours
Duration: 4-12 hours (may increase with dose)
Time to peak, plasma: 0.8-2 hours



NPH:Onset 1-2 hours, Peak: 4-12 hours
Duration: 18-24 hours
Time to peak, plasma: 6-12 hours

each increase not ot exceed 3-5U propotional to original dosage